So, called by Google search, the best example of MathJax web page:

https://sitesuserguide.stanford.edu/build/working-text-editor/mathjax-displaying-math-notation-your-page

1. enabling Chrome "Menu/Settings/MoreTools/Reading Mode", 
   allows user to read aloud the selected text,
   but reader does not stop after highlight.

2. reader does not understand fraction:
   x = {-b \pm \sqrt{b^2-4ac} \over 2a}.

3. Highlighting a fragment of page which contains an expression, does not highlight these expression, making a "spagetty highlight".

4. MathJax \begin{array} apparenly is not understood and skipped in combined generic reader:

For example:

\begin{array} {|r|r|}
\hline Space & City & Relationships & Graph  & Status \\ \hline 
(\mathbb{R}^{10} & 0.0735 & 0.0543 & 0.0917 & 0.0653 \\ \hline 
... 

5. When tabbing expressions, right clicking and selecting MathJax "Activate" all expressions are suddenly disappear from the page and the page begins useless.

6. Fortunately, MJ tabbing does not interfere with generic reader.er.

7. This is a MathJax v3.2.2. A bit old.
 
The test conducted on Chrome
Version 152.0.7977.64 (Official Build) (x86_64)
usually, by enabling "Menu/Settings/MoreTools/Reading Mode"